Artikel
Multicenter experience in the endovascular treatment of ruptured and unruptured intracranial aneurysms using the WEB (Woven Endobridge) device
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Veröffentlicht: | 9. Juni 2017 |
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Objective: The safety and efficacy of the Woven EndoBridge (WEB) device for the treatment of cerebral aneurysms has been investigated in several studies. Our objective was to report the experience of two neurovascular centers with the WEB device in the treatment of broad based intracranial aneurysms, including technical feasibility, safety, as well as short and mid-term angiographic and clinical follow-up-results.
Methods: We performed a retrospective analysis of all ruptured and unruptured aneurysms that were treated with a WEB device (WEB Single-Layer and Single-Layer Sphere) delivered through VIA 21, 27 and 33 catheters between August 2014 and November 2016. Primary outcome measures included the feasibility of the implantation and the angiographic outcome at 3- and 12-month follow-up. Secondary outcome measures included the clinical outcome at discharge and procedural complications.
Results: 96 aneurysms in 95 patients, including 35 ruptured aneurysms, were planned for treatment with the WEB device. The median age of patients was 57 years (range, 28-89 years). Implantation of the WEB was successful in 92. Procedural complications occurred in 6/96 (6.3%) of those 5 were thromboembolic events compared to one intraprocedural rupture. Angiographic follow-up at 3 months was available for 56/96 (58.3 %) aneurysms to date showing a sufficient aneurysm occlusion in 40/56 (71.4%) cases. At the second follow-up carried out 12 months post treatment the rate of sufficient aneurysmal occlusion improved to 88.9% (24/27 aneurysms). Retreatment was necessary in 13 aneurysms to date.
Conclusion: The WEB device offers a safe and effective treatment option for otherwise difficult to treat broad based intracranial aneurysms without the need of a dual antiplatelet therapy.