gms | German Medical Science

66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Friendship Meeting mit der Italienischen Gesellschaft für Neurochirurgie (SINch)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

7. - 10. Juni 2015, Karlsruhe

Artikel

Artikel empfehlen

Early postoperative magnet-resonance tomography after resection of cerebral metastases

Meeting Abstract

Suche in Medline nach

  • Marcel A. Kamp - Neurochirurgische Klink
  • Philipp J. Slotty - Neurochirurgische Klink,; Division of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada
  • Marion Rapp - Neurochirurgische Klink
  • Hans-Jakob Steiger - Neurochirurgische Klink
  • Bernd Turowski - Institut für diagnostische und interventionelle Radiologie, Medizinische Fakultät, Heinrich-Heine-Universität, Düsseldorf, Düsseldorf, Deutschland
  • Michael Sabel - Neurochirurgische Klink

Deutsche Gesellschaft für Neurochirurgie. 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Karlsruhe, 07.-10.06.2015. Düsseldorf: German Medical Science GMS Publishing House; 2015. DocMI.15.02

doi: 10.3205/15dgnc355, urn:nbn:de:0183-15dgnc3553

Veröffentlicht: 2. Juni 2015

© 2015 Kamp et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: In contrast to malignant gliomas, the impact of an early postoperative MRI after surgery of cerebral metastasis is still unclear. The present study analyses early MRI-based postoperative resection controls and incidence of in-brain-progression in 116 patients suffering from overall 130 cerebral metastases.

Method: Extent of surgical resection was verified by an early postoperative contrast-enhanced 1,5T-MRI within 72 hours after surgery and correlated with in-brain-progression, leptomeningeal carcinomatosis and progression free survival.

Results: MRI confirmed complete resection was seen in 80 / 130 metastases (61.5). In 24 metastases (18.5%) no final decision on degree of resection could be made. Residual tumour was seen in 26 cases (20 %). Local in-brain-progression was observed in 40 / 130 (30.8%) cases. The incidence of in-brain progression significantly correlated with dural contact of the metastasis (p < .05) and residual tumour on early postoperative MRI (p < .0001). The odd's ratio for local recurrence with residual tumor is 8.2 fold compared to no residual tumor on postoperative MRI.

Conclusions: Residual tumour after metastasis extirpation was shown in nearly 20 % of patients by an early postoperative MRI and significantly correlated with local in-brain-progression. Furthermore, dural contact of cerebral metastases was identified as risk factor for local recurrence. Further studies are mandatory to clearly identify the incidence of incomplete resections of cerebral metastases and their oncologic impact. An early postoperative MRI after resection of cerebral metastases is recommended as residual tumor promotes local recurrence.