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66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Friendship Meeting mit der Italienischen Gesellschaft für Neurochirurgie (SINch)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

7. - 10. Juni 2015, Karlsruhe

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Magnetic resonance imaging at 7 Tesla for neurosurgical patients – experience from 232 cases

Meeting Abstract

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  • Tobias Schoemberg - Klinik für Neurochirurgie, Universitätsklinikum Essen
  • Philipp Dammann - Klinik für Neurochirurgie, Universitätsklinikum Essen
  • Oliver M. Müller - Klinik für Neurochirurgie, Universitätsklinikum Essen
  • Mark E. Ladd - Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen; Abteilung Medizinische Physik in der Radiologie, Deutsches Krebsforschungszentrum Heidelberg
  • Ulrich Sure - Klinik für Neurochirurgie, Universitätsklinikum Essen
  • Karsten H. Wrede - Klinik für Neurochirurgie, Universitätsklinikum Essen

Deutsche Gesellschaft für Neurochirurgie. 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Karlsruhe, 07.-10.06.2015. Düsseldorf: German Medical Science GMS Publishing House; 2015. DocDI.04.01

doi: 10.3205/15dgnc111, urn:nbn:de:0183-15dgnc1119

Veröffentlicht: 2. Juni 2015

© 2015 Schoemberg et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

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Objective: To investigate the feasibility of ultra-high-field 7 Tesla (T) magnetic resonance imaging (MRI) in a clinical setup for various neurosurgical pathologies.

Method: This feasibility study prospectively evaluates application of 7 T MRI in a cohort of neurosurgical patients suffering from various pathologies since June 2008. The local university institutional review board approved the study, and written informed consent was obtained before each examination. Images were acquired on a 7T whole-body scanner using a commercial 32-channel head coil, a commercial 8-channel head coil, a custom-built 8-channel head coil, and a custom-built 8-channel body coil. Acquired sequences used for anatomical imaging included MPRAGE, FLASH-TOF, FLAIR, SWI, T2, PD, T2*, VIBE, and TWIST. For functional imaging, 2D-EPI and 3D-EPI were utilized.

Results: Scans could be successfully completed in 227 neurosurgical patients suffering from various pathologies without any problems or adverse effects. Only in 4 cases did the protocol have to be shortened because of claustrophobia, and there was a technical scanner failure in one case. The study group comprised 120 male and 112 female patients with a mean age of 47.6 years (19 - 82 years) and a mean body weight of 77 Kg (38 - 120 Kg). Scanning time varied between 19 to 130 minutes depending on the pathology (mean 65 minutes). The majority of patients suffered from cavernomas (n=55), gliomas (n=48), aneurysms (n=34), or AVMs (n=25). Anatomical brain imaging showed best results in SWI, FLAIR, and MPRAGE sequences. Aneurysms and arterial vascular malformations were depicted with excellent quality using a customized TOF sequence and in MPRAGE. Ultra-high-resolution functional imaging for block design and resting state design could be performed using a customized 2D-EPI and 3D-EPI sequence with robust results.

Conclusions: Ultra-high-field 7 T MRI examination was well tolerated by neurosurgical patients and provided superb image quality for most pathologies. Visualization of cerebral vascular pathologies with TOF and MPRAGE is an excellent candidate for first routine clinical application.