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66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Friendship Meeting mit der Italienischen Gesellschaft für Neurochirurgie (SINch)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

7. - 10. Juni 2015, Karlsruhe

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Durability of hearing preservation and regeneration capacity of the cochlear nerve following vestibular schwannoma surgery

Meeting Abstract

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  • Christian Scheller - Department of Neurosurgery, University of Halle-Wittenberg, Germany; Translational Centre for Regenerative Medicine (TRM), University of Leipzig, Germany
  • Andreas Wienke - Institute of Medical Epidemiology, Biostatistics, and Informatics, University of Halle-Wittenberg, Germany
  • Marcos Tatagiba - Department of Neurosurgery, University of Tübingen, Germany
  • Alireza Gharabaghi - Department of Neurosurgery, University of Tübingen, Germany
  • Kristofer F. Ramina - Department of Neurosurgery, University of Tübingen, Germany
  • Oliver Ganslandt - Department of Neurosurgery, University of Erlangen-Nuremberg, Germany
  • Barbara Bischoff - Department of Neurosurgery, University of Erlangen-Nuremberg, Germany
  • Cordula Matthies - Department of Neurosurgery, Würzburg University Hospital, Germany
  • Thomas Westermaier - Department of Neurosurgery, Würzburg University Hospital, Germany
  • Gregor Antoniadis - Department of Neurosurgery, Bezirkskrankenhaus Günzburg, University of Ulm, Germany
  • Maria Teresa Pedro - Department of Neurosurgery, Bezirkskrankenhaus Günzburg, University of Ulm, Germany
  • Veit Rohde - Department of Neurosurgery, University of Göttingen, Germany
  • Kajetan von Eckardstein - Department of Neurosurgery, University of Göttingen, Germany
  • Thomas Kretschmer - Department of Neurosurgery, Evangelisches Krankenhaus, University of Oldenburg, Germany
  • Johannes Zenk - Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen-Nuremberg, Germany
  • Christian Strauss - Department of Neurosurgery, University of Halle-Wittenberg, Germany

Deutsche Gesellschaft für Neurochirurgie. 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Karlsruhe, 07.-10.06.2015. Düsseldorf: German Medical Science GMS Publishing House; 2015. DocMO.08.09

doi: 10.3205/15dgnc037, urn:nbn:de:0183-15dgnc0373

Veröffentlicht: 2. Juni 2015

© 2015 Scheller et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: The purpose of this research was to examine the durability of hearing preservation and the regeneration capacity of the cochlear nerve following vestibular schwannoma (VS) surgery in a prospective study.

Method: A total of 112 patients were recruited for a randomized multicenter trial between January 2010 and April 2012 in order to investigate the efficacy of prophylactic nimodipine treatment versus no prophylactic nimodipine treatment in VS surgery. For the present investigation both treatment groups were pooled to compare hearing abilities in the early postoperative course and one year after the surgery. Hearing was examined by pure-tone audiometry with speech discrimination, which were performed preoperatively, in the early postoperative course and 12 months after surgery and subsequently classified by a blinded otorhinolaryngologist using the Gardner-Robertson scale.

Results: Hearing ability at two time points was compared by evaluation in the early postoperative course and one year after surgery in 102 patients. Chi-square-test showed a very strong association between the two measurements in all 102 patients (p<0.001), and in the subgroup of 66 patients with preserved cochlear nerve (p<0.001).

Conclusions: There is no significant change of cochlear nerve function between the early postoperative course and one year after VS surgery. The result of hearing performance as evaluated in early postoperative audiometry after VS surgery seems to be a reliable prognosticator for future hearing ability.