gms | German Medical Science

55. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
1. Joint Meeting mit der Ungarischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

25. bis 28.04.2004, Köln

Influence of high age and associated comorbidity on functional outcome of posterior lumbar interbody fusion (PLIF) for degenerative pseudolisthesis

Einfluss höheren Lebensalters und assoziierter Komorbidität auf das funktionelle Outcome der posterioren lumbalen interkorporellen Fusion (PLIF) bei degenerativer Pseudolisthese

Meeting Abstract

Suche in Medline nach

  • corresponding author Kai-Michael Scheufler - Abt. Allgemeine Neurochirurgie, Neurochirurgische Klinik, Universitätsklinikum Freiburg, Freiburg
  • V. Vougioukas - Abt. Allgemeine Neurochirurgie, Neurochirurgische Klinik, Universitätsklinikum Freiburg, Freiburg

Deutsche Gesellschaft für Neurochirurgie. Ungarische Gesellschaft für Neurochirurgie. 55. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 1. Joint Meeting mit der Ungarischen Gesellschaft für Neurochirurgie. Köln, 25.-28.04.2004. Düsseldorf, Köln: German Medical Science; 2004. DocDI.03.10

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Veröffentlicht: 23. April 2004

© 2004 Scheufler et al.
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To investigate the specific influence of age and associated medical comorbidity (e.g., cardiopulmonary diseases, diabetes) on clinical, social and radiological results in patients ≥65 years of age with significant comorbidity (group A) receiving PLIF for mono- or bisegmental degenerative lumbar pseudolisthesis (DLP; Meyerding grades I&II) as compared to a reference population (≤65 years, no significant comorbidity; group B).


A total of 62 consecutive patients (20 patients ≥65 years) undergoing mono- or bisegmental PLIF using pedicle screw-rod systems and interbody PEEK cages were prospectively evaluated using the AAOS lumbar spine outcomes instrument and Roland-Morris low back pain questionnaire. Following preoperative evaluation, functional outcome was assessed by 3, 6 and 12 months. Progression to solid bony fusion was evaluated by radiographic controls at 6 and 12 months.


In group A, 10 patients (50%) experienced perioperative problems such as delayed wound healing (mainly due to significant obesity), 4 patients (20%) developed clinical symptoms from early adjacent segment degeneration. In contrary, only 1 (significantly obese) patient of group B experienced delayed wound healing; early degeneration of adjacent segments was not observed. All patients (groups A and B) went on to achieve solid bony fusion of the instrumented segments. AAOS and Roland-Morris scores improved significantly (P<0.05) in both groups, with slightly better results in the control group (P>0.05).


While perioperative risks increased significantly in patients ≥65 years with significant comorbidity (especially in obese patients), functional outcomes of PLIF for DLP in this group were comparable to the control group. In monosegmental fusion, clinically manifest early adjacent segment degeneration was found in elderly patients only. Despite the specific problems encountered in elderly patients, PLIF for DLP appears to be a viable treatment option even in high-aged patients with significant medical comorbidity.