Artikel
Digital pupillometry with PupilX in a normal population
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Veröffentlicht: | 1. März 2016 |
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Gliederung
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Purpose: The aim of this study was to evaluate the pupil size of normal subjects at different illumination levels to establish a nomogram for pupil size and anisocoria in a healthy population under well-defined measurement conditions with a novel pupillometer.
Methods: Pupil size of healthy study participants was measured with infrared-video PupilX pupillometer (MEye Tech GmbH) at 5 different illumination levels (0, 0.5, 4, 32 and 250 lux). Measurements were performed by the same person during a measurement period of 3 seconds with 90 images with an absolute linear camera resolution of approximately 20 pixel per mm.
Results: This cross-sectional study analysed 490 eyes of 245 patients (mean age 51.9 ± 18.3 years, range 6-87 years). On average, the mean pupil diameter decreased for both eyes with light intensity with 5.39 mm ± 0.10 for 0 lux, 5.20 mm ± 0.13 for 0.5 lux, 4.70 mm ± 0.16 for 4 lux, 3.74 mm ± 0.18 for 32 lux and 2.84 mm ± 0.13 for 250 lux illumination. Percentage of patients with anisocoria increases with age. The amount of anisocoria is higher under scotopic and mesopic conditions.
Conclusion: This study provides reference values concerning age- and light-related pupil size and anisocoria as a baseline for future patient studies.