Artikel
Microcirculation in patients with primary and recurrent Dupuytren's disease: a prospective hyperspectral imaging study
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Autoren
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Inga Langner
- Klinik und Poliklinik für Orthopädie, Greifswald, Germany
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Esther Henning
- Methoden der Community Medicine, Greifswald, Germany
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Claudia Sicher
- Institut für Hygiene und Umweltmedizin, Greifswald, Germany
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Fabian Lorenz
- Klinik und Poliklinik für Orthopädie, Greifswald, Germany
| Veröffentlicht: | 6. Oktober 2022 |
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Gliederung
Text
Objectives: Microcirculation of the hand was evaluated in patients with primary and recurrent Dupuytren's disease (DD) before partial fasciectomy using hyperspectral imaging (HIS). We hypothesized that both populations differ in the hand's microperfusion.
Method: Before partial fasciectomy in an inpatient university hospital setting 35 patients with DD (primary and recurrent) and were investigated using hyperspectral imaging (HSI). Superficial oxygenation (StO2) and deep oxygenation (NIR), tissue hemoglobin index (THI) and tissue water index (TWI) were assessed at three regions of interest (ROI). 10 participants without any hand condition served as controls. Resected tissue was histologically evaluated and graded according to Luck.
Results: The mean age of the patients was 63.5 years (±8.5), 6 patients were female, and 54% had recurrent DD. Both groups did not show any significant difference in preoperative measured StO2, THI and TWI, with only the preoperative NIR being higher in the primary group in all three ROI. In the resected tissue we observed no histological differences between primary and recurrent DD.
Conclusion: HSI allows the non-invasive quantitative assessment of perfusion parameters in patients with DD before partial fasciectomy. Differences in NIR is caused by scar tissue from previous sugery and could be accused of wound healing disorders in recurrent DD. (EbM-Level IIa)
