gms | German Medical Science

131. Kongress der Deutschen Gesellschaft für Chirurgie

Deutsche Gesellschaft für Chirurgie

25.03. - 28.03.2014, Berlin

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The Mechanism of Vascularized Lymph Node Transfer for Lymphedema – Natural Lymphatico-Venous Drainage

Meeting Abstract

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  • Leila Kolios - BG Unfallklinik Ludwigshafen, Klinik für Hand-, Plastische und Rekonstruktive Chirurgie, Ludwigshafen
  • Jung-Ju Huang - Chang Gung Memorial Hospital, Department of Plastic and Reconstructive Surgery, Taoyuan
  • Chih-Wei Wu - Chang Gung Memorial Hospital, Department of Plastic and Reconstructive Surgery, Taoyuan
  • Chin-Yu Yang - Chang Gung Memorial Hospital, Department of Plastic and Reconstructive Surgery, Taoyuan
  • Chia-Yu Lin - Chang Gung Memorial Hospital, Department of Plastic and Reconstructive Surgery, Taoyuan
  • Ulrich Kneser - BG Unfallklinik Ludwigshafen, Klinik für Hand-, Plastische und Rekonstruktive Chirurgie, Ludwigshafen
  • Ming-Huei Cheng - Chang Gung Memorial Hospital, Department of Plastic and Reconstructive Surgery, Taoyuan

Deutsche Gesellschaft für Chirurgie. 131. Kongress der Deutschen Gesellschaft für Chirurgie. Berlin, 25.-28.03.2014. Düsseldorf: German Medical Science GMS Publishing House; 2014. Doc14dgch548

doi: 10.3205/14dgch548, urn:nbn:de:0183-14dgch5489

Veröffentlicht: 21. März 2014

© 2014 Kolios et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

Text

Introduction: Vascularized lymph node flap transfer for treatment of upper and lower limb lymphedema has already shown promising results. This study was to investigate the mechanism of lymph drainage of vascularized lymph node flap both experimentally and clinically.

Material and methods: In experimental part, eighteen Sprague Dawley rats with 36 flaps were injected of indocyanine green to a cutaneous flap (Group Ia, Rat NLN Flap), a groin lymph node flap edge (Group Ib, Rat-SC Flap) or directly into lymph node (Group Ic, Rat-LN Flap), n=12 each. Fluorescence was activated by the infrared at a wavelength of 760 nm and detected by a camcorder. In clinical part, 12 cutaneous flaps were injected with ICG from flap edge as the Group IIa (Clin-NLN Flap), and 24 vascularized lymph node flaps were injected either in flap margin (Group IIb, Clin-sc Flap, n=12) or the exposed lymph node directly (Group IIc, Clin –

LN Flap, n=12).

Results: There was no drainage of ICG into the pedicle vein in Group Ia. The mean latency of fluorescence drained into the pedicle vein was 153.5 ± 129 second in Group Ib, and 12.8 ± 8.1 second in Group Ic. (p<0.01) There was no visible fluorescence drainage into the pedicle vein in Group IIa. The mean latency of fluorescence detected in the pedicle vein was 346.5 ± 248.9 seconds in Group IIb, and 23.5 ± 27.1 seconds in Group IIc. (p<0.01).

Conclusion: The vascularized lymph node flap drains the lymph directly into the pedicle vein, both experimentally and clinically.