Artikel
Bipolar radiofrequency-induced thermofusion of intestinal anastomoses – In vivo evaluation of a new anastomosis technique in an experimental study
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Autoren
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Christoph Holmer
- Charité - Campus Benjamin Franklin, Chirurgische Klinik I, Berlin
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Matthias Kröger
- Technische Universität Berlin, Fachgebiet Medizintechnik, Berlin
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Hanno Winter
- Technische Universität Berlin, Fachgebiet Medizintechnik, Berlin
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Alexandra Nagel
- Charité - Campus Benjamin Franklin, Chirurgische Klinik I, Berlin
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Annika Jaenicke
- Technische Universität Berlin, Fachgebiet Medizinische Biotechnologie, Berlin
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Roland Lauster
- Technische Universität Berlin, Fachgebiet Medizinische Biotechnologie, Berlin
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Marc Kraft
- FG Medizintechnik, Sekretariat SG11, Berlin
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Heinz J. Buhr
- Charité - Campus Benjamin Franklin, Chirurgische Klinik I, Berlin
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Jörg-Peter Ritz
- Helios Kliniken Schwerin, Klinik für Allgemein- und Viszeralchirurgie, Schwerin
| Veröffentlicht: | 26. April 2013 |
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Gliederung
Text
Introduction: Since vessel sealing technology depends on the fusion of collagen fibers abundantly present in the intestinal wall, it should also be possible to create intestinal anastomoses by bipolar radiofrequency-induced thermofusion. Previous results of our study group confirmed the feasibility to fuse intestinal tissue using bipolar radiofrequency-induced thermofusion ex vivo. The aim of this study was now to evaluate the efficacy of fusing intestinal tissue in vivo by bipolar radiofrequency-induced thermofusion.
Material and methods: In seventy male Wistar rats a blind bowel originated from the cecum was closed either by bipolar radiofrequency-induced thermofusion (n = 44) or conventional suture (n = 26). Six, 48, 96 h and 2 weeks after the procedure cecum bursting pressure was measured.
Results: 43 of 44 (97,7%) thermofused and all sutured cecal stumps were primarily tight and leakage-proof. The operative time was comparable in both groups without significant differences (thermofusion 9 min vs. conventional suture 10 min). Both groups showed progressive increases in bursting pressure over the postoperative period (Figure 1 [Fig. 1]). The mean bursting pressure for thermofusion was 53, 48, 59 and 79 mmHg after six, 48, 96 h and 2 weeks, respectively, and did not differ from the hand-sutured group (Figure 1 [Fig. 1]).
Conclusion: These results confirm that the closure of the cecal stump with bipolar radiofrequency-induced thermofusion is a safe and feasible method in this in vivo model. The stability of the induced thermofusion showed no differences compared to conventional suture. Bipolar radiofrequency-induced thermofusion of intestinal tissue seems to be an innovative approach for achieving gastrointestinal anastomoses.
