Artikel
Quantum dot-integrated nanowire arrays for photovoltaic retinal stimulation in the near-infrared
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Autoren
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Tarık Safa Kaya
- Department of Material Science and Engineering, Koç University, Istanbul, Turkey
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H. Nur Kaleli
- Research Center for Translational Medicine, Koç University, Istanbul, Turkey
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R. Balamur
- Department of Electrical and Electronics Engineering, Koç University, Istanbul, Turkey
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A. Önal
- Department of Biomedical Science and Engineering, Koç University, Istanbul, Turkey
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Ç. Pehlivan
- Research Center for Translational Medicine, Koç University, Istanbul, Turkey
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U. B. Çalışkan
- Department of Electrical and Electronics Engineering, Koç University, Istanbul, Turkey
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R. Mohajeri
- Department of Electrical and Electronics Engineering, Koç University, Istanbul, Turkey
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A. Şahin
- Research Center for Translational Medicine, Koç University, Istanbul, Turkey
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M. Hasanreisoglu
- Research Center for Translational Medicine, Koç University, Istanbul, Turkey
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S. Nizamoglu
- Department of Electrical and Electronics Engineering, Koç University, Istanbul, Turkey
| Veröffentlicht: | 9. Mai 2025 |
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Gliederung
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Objective: To demonstrate efficient, near-infrared-responsive photovoltaic bioelectronic devices with sub-micron thickness for retinal photostimulation.
Materials and Methods: Nanowire arrays were grown via chemical bath deposition and integrated with infrared-sensitive quantum dots to form a photovoltaic device. Ruthenium oxide (RuO₂) was employed as the return electrode. The device's structural and photoelectrochemical performance, as well as its in-vitro biocompatibility, were thoroughly characterized. Photostimulation of the retina is currently being evaluated through multi-electrode array (MEA) recordings.
Results: The device exhibited efficient light-to-current conversion, achieving a mean charge injection density of 20.96 µC cm⁻² under 780 nm near-infrared (NIR) illumination at a light intensity of 89 mW cm⁻². This performance is 20 times higher than that of a device without the RuO₂ layer. The device demonstrated good biocompatibility, verified through MTT and LDH leakage assays, and exhibited good stability during accelerated aging and sterilization tests.
Discussion: The photogenerated charges are sufficient for retina stimulation. These characteristics suggest the device is a promising candidate for subretinal implantation.
Acknowledgment: This study was funded by the European Union (ERC, MESHOPTO, 101045289). Views and opinions expressed are, however, those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.
