gms | German Medical Science

Artificial Vision 2019

The International Symposium on Visual Prosthetics

13.12. - 14.12.2019, Aachen

Suprachoroial retinal stimulation using temporally interfering electric fields: a simulation study

Meeting Abstract

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  • Yasuo Terasawa - Artificial Vision Institute, Nidek Co., Ltd, Gamagori/J; Materials Science, Nara Institute of Science and Technology/J
  • H. Tashiro - Materials Science, Nara Institute of Science and Technology; Department of Health Sciences, Kyushu University/J
  • J. Ohta - Materials Science, Nara Institute of Science and Technology/J

Artificial Vision 2019. Aachen, 13.-14.12.2019. Düsseldorf: German Medical Science GMS Publishing House; 2019. Doc19artvis11

doi: 10.3205/19artvis11, urn:nbn:de:0183-19artvis113

Veröffentlicht: 10. Dezember 2019

© 2019 Terasawa et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe



Objective: Recently electrical stimulation using temporally interfering electric fields was proposed as a method to stimulate neural tissues distant from stimulation electrodes. The purpose of this study is to investigate the feasibility of temporally interfering electric fields as a method to selectively stimulate retinal neurons distant from electrodes suprachoroidally.

Materials and methods: Two-dimensional eye model consisting of sclera, choroid, retina, vitreous body and surrounding tissue was developed. Two-channel electrode array was placed in the sclera. Sinusoidal current waves were applied to the two electrodes. The frequencies of sinusoidal waves were 2 kHz for ch1 and 2.05 kHz for ch2 respectively. Evoked current distribution inside the eye was calculated and visualized by numerical analysis software (COMSOL Multiphysics).

Results: For the Y components of current vector (the Y direction is perpendicular to the retina), a region with high amplitude of current envelope was observed both in the choroid and in the retina between two electrodes. For the X components (the X direction is parallel to the retina), high-amplitude area was observed in the sclera between two electrodes.

Discussion: Simulation results suggested that electrical stimulation of retinal neurons distant from the electrodes was feasible by temporally interfering electric fields.