gms | German Medical Science

VI. International Symposium on AMD – Age-Related Macular Degeneration – Emerging Concepts – Exploring known and Identifying new Pathways

11. - 12.09.2015, Baden-Baden

Monitoring of photoreceptor survival by AO-SLO

Meeting Abstract

Suche in Medline nach

  • Wolf M. Harmening - Bonn
  • N. Domdei - Bonn
  • L. Sincich - Bonn
  • F.G. Holz - Bonn

VI. International Symposium on AMD – Age-Related Macular Degeneration – Emerging Concepts – Exploring known and Identifying new Pathways. Baden-Baden, 11.-12.09.2015. Düsseldorf: German Medical Science GMS Publishing House; 2015. Doc15amd28

doi: 10.3205/15amd28, urn:nbn:de:0183-15amd286

Veröffentlicht: 1. Oktober 2015

© 2015 Harmening et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.


Gliederung

Text

With the adaptive optics scanning laser ophthalmoscope (AO-SLO), individual retinal photoreceptor cells can be made visible in the living human eye. Combined with real-time eye tracking and fast optical switches, the AO-SLO acts as the technological platform to also allow micro-stimulation of targeted retinal areas. First psychophysical data reveal that single photoreceptor cells can be indeed tested repeatedly and in isolation. The talk discusses results studying the relationship between visual function of single cone photoreceptor cells and their reflection properties in AO-SLO images in healthy subjects. From that it becomes apparent that we cannot simply infer visual function from visible structure, and that we still have to learn how to interpret AO-SLO images showing conspicuous features. Adding some means of functional tests of photoreceptor health will be especially important when judging photoreceptor integrity in cases of retinal disease.