Artikel
Rhinoscleroma endemic in Egypt with atypical presentations "continue"
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Veröffentlicht: | 26. April 2017 |
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Gliederung
Abstract
Rhinoscleroma: endemic in Egypt with some atypical presentations
Scleroma or Rhinoscleroma is a progressive granulomatous disease affecting the nose and later extending into the nasopharynx and oropharynx, the larynx and sometimes the trachea and bronchi. Laryngeal involvement may occur in almost 50% of cases and the disease is better designated as respiratory scleroma, rather than rhinoscleroma. The disease is caused by the Gram-negative bacillus, Klebsiella rhinoscleromatis, also known as Frisch bacillus. The characteristic histological features include granulomatous tissue infiltrates in the submucosa, characterized by the presence of plasma cells, lymphocytes and eosinophils. Besides, there are scattered large foam cells (Mikulicz cells) which have a central nucleus and a vacuolated cytoplasm containing bacilli and Russel bodies. It is seen mainly in central and south-eastern Europe, North Africa, the Indian subcontinent, Indonesia and Central and South America.
It is endemic in Egypt and especially in Fayoum.
We reported four cases of atypical presentation among patients presented to (Fayoum university hospitals) in the form of:
- 1.
- A large vocal fold polyp with normal subglottis( the most common site for laryngeal affection) and free nasal cavity.
- 2.
- Large nasopharyngeal mass looks like lymphoma with free nasal cavity.
- 3.
- Nasal polyp filling the maxillary sinus cavity on both sides with free nasal cavity.
- 4.
- Bilateral septal swelling occupying most of the nasal cavity.
Unterstützt durch: This is continuation to my work presented on 2015 in the 86th Annual Meeting with additional 2 cases.
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