gms | German Medical Science

21st Annual Meeting of the German Retina Society and 8th Symposium of the International Society of Ocular Trauma (ISOT)

German Retina Society
International Society of Ocular Trauma

19.06. - 22.06.2008, Würzburg

About the Timing of Primary Surgery of the Open-Globe Injury Involving Posterior Segment

Meeting Abstract

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  • Michail Shishkin - Moscow/Russia
  • V. Mironov - Moscow/Russia

Retinologische Gesellschaft. International Society of Ocular Trauma. 21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem 8. Symposium der International Society of Ocular Trauma. Würzburg, 19.-22.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocISOTRG2008V038

The electronic version of this article is the complete one and can be found online at:

Published: June 18, 2008

© 2008 Shishkin et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



The timing of performing the primary surgery (PS) of the open-globe injury (OGI) involving posterior segment is a matter of dispute. Some specialists support a stage-by-stage approach: immediate PS with further vitreoretinal surgery procedure (VRS) at a vitreoretinal centre, if required. As for the opponents to the above approach, they recommend delayed PS with simultaneous reconstructing VRS.Purpose of the research: Determination of the optimal timing of PS with OGI involving posterior segment.

Research materials and methods: The work was performed in accordance with International Recommendations on Medical-and-Biologic Research. Methods applied were clinic and cytologic research. Experimental material groups: Groups I, II, III and IV – rabbits’ eyes to simulate standard OGI approximated to ocular war injuries with localization in zone II. After 12, 24, 48, 72 hrs following the injury PS was applied, accordingly. On the 30th day following the injury enucleation was performed.

Research results: The research showed that with the animal material of Groups II and III fibrinous-and-inflammatory and proliferation responses of intraocular structures were less expressed, as compared to animal material of Groups I and IV.

Conclusion: Both the PS for OGI involving posterior segment after over 2 days and surgery treatment within the first 12 hrs following the injury affect the course of eye wound healing.