gms | German Medical Science

81st Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

12.05. - 16.05.2010, Wiesbaden

Endoscopic Hypophysectomy

Meeting Abstract

  • corresponding author Spyros Papaspyrou - Evangelsimos Hospital, Athens, Greece
  • E. Siggounas - Evangelismos Hospital, Athens, Greece
  • G. Stranjalis - Evangelismos Hospital, Athens, Greece
  • E. Boviatsis - Evangelismos Hospital, Athens, Greece
  • D. Sakkas - Evangelismos Hospital, Athens, Greece

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 81. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Wiesbaden, 12.-16.05.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. Doc10hnod103

doi: 10.3205/10hnod103, urn:nbn:de:0183-10hnod1035

Published: April 22, 2010

© 2010 Papaspyrou et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Introduction: Endoscopic endonasal hypophysectomy constitutes a challenge and an opportunity for the Otolaryngologist who is more familiar with the anatomy of the nose and the adjacent structures in comparison with the neurosurgeons.

Methods: Last 15 years, 246 hypophysectomies have been performed in cooperation with neurosurgical department of our hospital. These patients presented mainly to the neurosurgery department. As otolaryngologistes, we performed the first step of procedure (opening of the sphenoid sinus, opening of the prominence of sella, and reaching the dura of the pituitary adenomas). The second step is continued with the presence and cooperation of the neurosurgeon. For the first 182 hypophysectomies a sublabial approach was performed with the use of a microscope. Subsequently, 22 hypophysectomies were performed with a combined approach (sublabial microscope-endoscope assisted). Lastly, the most recent 42 hypophysectomies, endonasal endoscopic 4-hands technique was applied.

Results: With all 3 techniques success rate did not significantly differ. Complication rate (hemorrhage, cerebrospinal fluid leak) was significantly lower in the endoscopic technique. Hospital stay was also significantly lower in endoscopic technique.

Conclusions: The advantages of endoscopic approach are: less traumatic, faster, panoramic view, angle-view with the use of different endoscopes, and possibility to explore the sella for residual tumor at the end of operation. Its disadvantages are the lack of three-dimenshion view and the need of an assistant to hold the endoscope.