gms | German Medical Science

78th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

16.05. - 20.05.2007, Munich

Perceptual and Acoustic Characteristics of Voice Changes in Reflux Laryngitis Patients

Meeting Abstract

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  • corresponding author Virgilijus Uloza - Department Otolaryngology, Kaunas University of Medicine, Kaunas, Lithuania
  • Ruta Pribuisiene - Department Otolaryngology, Kaunas University of Medicine, Kaunas, Lithuania

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 78. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.. München, 16.-20.05.2007. Düsseldorf: German Medical Science GMS Publishing House; 2007. Doc07hnod482

The electronic version of this article is the complete one and can be found online at:

Published: April 24, 2007

© 2007 Uloza et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



The aim of the study was to analyze and quantify voice characteristics of reflux laryngitis (RL) patients, to determine voice tests and voice-quality parameters of the most importance in the functional diagnostics of RL.

Methods: Voices of 108 RL patients and 90 healthy persons of control group were evaluated. Vocal function was assessed using a set of video laryngostroboscopic, perceptual, acoustic, aerodynamic and subjective voice quality measurements according to the protocol elaborated by the Committee on Phoniatrics of the ELS.

Results: The mean values of hoarseness (VAS assessment) and VHI were significantly higher (p<0.05) in the group of RL patients comparing to the controls. Objective voice assessment revealed a significant increase of the mean values of jitter, shimmer and normalized noise energy (NNE) along with a significant decrease of the pitch range, maximum frequency, phonetogram area (S) and maximum phonation time (MPT) in RL patients, both in male and female subgroups. According to the results of discriminant analysis, NNE, MPT, S and intensity range were determined as an optimum set for functional diagnostics of RL.

Conclusions: This study demonstrated that perceptual and subjective evaluation as well as objective measures of voice parameters document a deteriorated voice quality caused by RL. Deteriorated phonation pattern and voice-related problems lead to negative impact on patient’s everyday life and professional activities, as reflected by significantly increased values of VHI. Treatment of RL patients along with special medication and life style modifications should involve care of the patient’s voice. Consequently, assessment of the results of the treatment of RL patients should include monitoring of voice quality and VHI.