gms | German Medical Science

14. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie

Gesellschaft für Arzneimittelforschung und Arzneimittelepidemiologie

15.11. - 16.11.2007, Frankfurt am Main

Analysis of the impact of discount agreements on the medicinal product consumption using Contract Manager

Meeting Abstract

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Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie e.V. (GAA). 14. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie. Frankfurt am Main, 15.-16.11.2007. Düsseldorf: German Medical Science GMS Publishing House; 2007. Doc07gaa11

The electronic version of this article is the complete one and can be found online at:

Published: November 12, 2007

© 2007 Schröder-Bernhardi et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Aim of the study: The adoption of new legislation in the health service entails considerable changes in the consumption of medicinal products after only few months. Since April 1st, 2007, discount agreements based on the GKV-WSG (German Statutory Health Insurance Competition Enhancement Act) apply which were originally issued for 42 active ingredients. The analyses referenced here focus on the impact of these discount agreements on physicians, pharmacists, and patients.

Method: The data are based on prescriptions submitted with >99% coverage, presented on a monthly basis by regions and all individual health insurance companies. Quantitative data were completed by a survey conducted with physicians and patients selected at random.

Results: The discount agreements with defined manufacturers of generic products have a strong impact on the research conducted on the supply. The discount agreement of the AOK, one of Germany’s major statutory health insurance companies, alone has a considerable influence on the market share compared with the total market. The changes brought about can be clearly illustrated with the example of simvastatin: The 3 top manufacturers of generic products lost a market share of 18%, while the manufacturer with the discount agreement grew by 13%.

In an on-line survey conducted in 5/07, many physicians indicated that discount agreements had not yet led to a change in their prescribing behaviour. Most patients (51.5%) indicated that they expect “their” product to be prescribed for the future, too.

Conclusion: The new laws have had considerable consequences for physicians, patients, health insurance companies, and pharmaceutical manufacturers. Undesirable effects include an increase in non-compliance and a lower persistence in courses of treatment.