gms | German Medical Science

104th DOG Annual Meeting

21. - 24.09.2006, Berlin

Chances for Ukrainian patients with epithelial malignant tumors (EMT) of eyelids at cryosurgery

Meeting Abstract

  • A. S. Bouiko - Filatov Institute of Eye Diseases, Odessa, Ukraine
  • I. A. Safronenkova - Filatov Institute of Eye Diseases, Odessa, Ukraine
  • V. A. Yelagina - Filatov Institute of Eye Diseases, Odessa, Ukraine

Deutsche Ophthalmologische Gesellschaft e.V.. 104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft (DOG). Berlin, 21.-24.09.2006. Dsseldorf, Kln: German Medical Science; 2006. Doc06dogSA.08.12

The electronic version of this article is the complete one and can be found online at:

Published: September 18, 2006

© 2006 Bouiko et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




The important priority in the creation of new methods of treatment is the reduction of negative influence on the quality of patient’s life. This is especially actual for elderly people. The substantial progress has been achieved in treatment of cataract, glaucoma, distrophic diseases. However since 1827 from times of Artur Jakob the treatment of EMT remains without changes - surgery. The surgical method becomes more complicated as well as operating and post-operating problems of a patient. New modifications of cryosurgery of EMT were developed in the Ukraine and Germany in the last 15-20 years.

To reduce the influence of the treatment on the quality of patient’s life on the basis of the modified cryotechnology


The retrospective analysis of cryosurgery was carried out for 1135 patients with EMT of eyelids in stages I-II (basal cell and squamous cell cancer) in a period from 1986 to 2005. Medin age of patients was 64 years, minimum 29, maximum – 96 years. There were more than 723 (63,7%) patients older than 60 years. For treatment the original cryoequipment and method were used. They provided the forecast (coefficient of determination 0,76) results of single session of treatment. The remote results of treatment were considered at 714 patients for period 1988-2000. The analysis - January-February, 2006.


Middle area of tumor was 112,9116,8SD 2 , from 4,0 2 to 1040,0 2. The median time of cryodestruction was 145 s, minimum 25, maximum 1620 s. Time of the operation together with preparation was from 8 to 15 minutes. Additional session of treatment in terms from 7 to 300 days was needed only for 129 (11,4%) patients. The treatment was performed in 878 (77,4%) patients in the day they turned to ophthalmooncologist. The number of recurrences was 33 (4,6%) at the terms of follow-up period of 714 patients in terms of more than 5 years.


At cryosurgical treatment of EMT of eyelids most patients of Ukraine have a chance to be cured in the day of primary visit of specialist for one 8-15 minute’s procedure of cryodestruction. Patients easily receive the procedure even at heavy general status and gladly continue it at numerous tumors. No subsequent reconstructive operations are required. We didn’t see any complication after cryosurgery during all time of our practice.