gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Multifocal electroretinography and OCT in segmental retinitis pigmentosa

Meeting Abstract

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  • corresponding author A. Karandish - Klinik für Augenheilkunde, Schlosspark-Klinik Berlin
  • R. Keuch - Klinik für Augenheilkunde, Schlosspark-Klinik Berlin
  • H. Bleckmann - Klinik für Augenheilkunde, Schlosspark-Klinik Berlin

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSA.12.03

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Karandish et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




Generalized retinal degenerations such as retinitis pigmentosa (RP) may manifest with focal retinal dysfunctions. These may be detected objectively by new electrophysical techniques, such as multifocal electroretinography or by OCT images.

Case report

A 33 years old female patient, showed bilateral caudal bone spiculae formations with corresponding cranial field defects in the static perimetry of the central visual field (Octopus) and in the kinetic perimetry (Goldmann).


Cone ERG were within the normal range. The multifocal cone ERG of the central 50° showed reduced amplitudes and prolonged latencies in the first-order response component. These findings corresponded to the area of the bone spiculae and scotoma. OCT images showed the displacement of pigmented retinal pigment epithelial (RPE) cells, which forward in to the inner layers of the neural retina. The retinal thickness was decreased in the areas of the retina affected by RP, and nearly normal in the unaffected area.


Multifocal ERG and OCT enables the detection of focal retinal cone dysfunction in segmental retinitis pigmentosa. these additional tools may aid in the diagnosis and classification of this disease.