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27th International Congress of German Ophthalmic Surgeons

15. to 17.05.2014, Nürnberg

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The use of microperimetry in the assessment of central retinal sensitivity in patients with pituitary adenomas (K)

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  • Monika Sarnat-Kucharczyk - University Center of Ophthalmology and Oncology, Department of Ophthalmology, Katowice, Poland
  • Ewa Mrukwa-Kominek - University Center of Ophthalmology and Oncology, Department of Ophthalmology, Katowice, Poland

27. Internationaler Kongress der Deutschen Ophthalmochirurgen. Nürnberg, 15.-17.05.2014. Düsseldorf: German Medical Science GMS Publishing House; 2014. DocPO 4.1

doi: 10.3205/14doc176, urn:nbn:de:0183-14doc1768

Published: May 5, 2014

© 2014 Sarnat-Kucharczyk et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Purpose: To evaluate if microperimetry can be an alternative to different perimetric tests in patients with pituitary adenoma. To assess the relationship between the central retinal sensitivity and contrast sensitivity. To evaluate the usefulness of microperimetry and contrast sensitivity testing as supporting methods of diagnosing expansion of pituitary adenomas.

Methods: The analyzed group consisted of 40 patients diagnosed with pituitary adenoma based on magnetic resonance imaging (MRI). Patients were divided into two groups based on the outcome of MRI of the pituitary gland:

  • Group 1 – microadenoma of the pituitary gland – tumors with diameter <1 cm
  • Group 2 – macroadenoma of the pituitary gland – tumors with diameter ≥1 cm

Patients were subjected to the following tests: perimetry (kinetic Goldmann and static Octopus, Haag-Streit), contrast sensitivity test (F.A.C.T., Stereo Optical) and microperimetry (Microperimetr MP-1, Nidek Technologies). The examined part of the central retina in microperimetric test was divided into four quadrants.

Results: The Mean Sensitivity (MS) of central retina in the microperimetric test was the lowest in upper-nasal quadrant (Group 1 = 16,01 dB, Group 2 = 8,65 dB) and the highest in lower-temporal quadrant (Group 1 = 17,8 dB, Group 2 =14,33 dB). Also reduction in contrast sensitivity was observed which was more significant in the second group – Average Patch scores: for 1,5 Cycles/Degree – Group 1 = 5,08, Group 2 = 3,54; for 3 Cycles/Degree – Group 1 = 5,39, Group 2 = 3,64; for 6 Cycles/Degree – Group 1 = 4,79, Group 2 = 2,95; for 12 Cycles/Degree – Group 1 = 3,24 Group 2 = 1,92; for 18 Cycles/Degree – Group 1 = 2,12 Group 2 = 0,94; p<0,05.

Conclusions: Microperimetry compared to other perimetric tests is a highly sensitive method for evaluating even the slightest changes in the sensitivity of the central retina. Microperimetry allows to detect changes in macular sensitivity which may not be recorded by other perimetric tests.

The relationship between the sensitivity of the central retina and the contrast sensitivity in patients with pituitary adenomas was observed.

Microperimetry and contrast sensitivity testing as non-invasive tests may provide additional tools to MRI in the diagnosis of optic pathway compression by pituitary adenomas.