gms | German Medical Science

27th German Cancer Congress Berlin 2006

German Cancer Society (Frankfurt/M.)

22. - 26.03.2006, Berlin

Results of a discrimination analysis between patients with breast- and colon carcinoma

Meeting Abstract

  • corresponding author presenting/speaker Matthias Kröz - Forschungsinstitut Havelhöhe, Berlin, Deutschland
  • Markus Reif - Institut für klinische Forschung, Berlin
  • Roland Zerm - Forschungsinstitut Havelhöhe, Berlin
  • Broder von Laue - Gemeinschaftspraxis, Öschelbronn
  • Dagmar Brauer - Forschungsinstitut Havelhöhe, Berlin
  • Christian Heckmann - Universität, Witten/Herdecke
  • Marion Debus - Forschungsinstitut Havelhöhe, Berlin
  • Christian Bartsch - Universität, Tübingen

27. Deutscher Krebskongress. Berlin, 22.-26.03.2006. Düsseldorf, Köln: German Medical Science; 2006. DocPE590

The electronic version of this article is the complete one and can be found online at:

Published: March 20, 2006

© 2006 Kröz et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Introduction: Psycho-oncological studies have shown that patients with different types of tumours show marked differences in the way they cope with their illness. So far there have been no studies which, apart from capturing standard psycho-oncological constructs such as social hyperadaptation or repression a.o., also record chronobiological markers. We examined to what extent patients with breast cancer (BCa) and colon cancer (CCa) differed from one another with regards to psycho-vegetative patterns.

Method: We carried out a conditional logistic regression to discriminate between 95 BCa- and 51 CCa-patients (♀: 31, ♂: 20); strata differentiated between gender and first or second questioning respectively. Beside age the scales considered were: The long version on endogenous regulation (eR: subscales for circulation, sleep-wake and digestion), the Hospital Anxiety & Depression Scale (A&D-HADS), the short questionnaires on self regulation and chronotypology (MfC). The analysis showed identical results for forward-, backward- and stepwise-selection. The most suitable model is chosen by comparing the c²-values of the hierarchically ordered models.

Results: Table 1 [Tab. 1] shows the characteristics of the groups. In the full model the depression and anxiety scales correlate with r=-0.53 and eR-sleep-wake with MfC with r=-0.35. Table 2 [Tab. 2] shows the three selected, highest discriminating scales which yield a multivariate logistic model with c²=14.8, p=0.002, R²=0.15.

Conclusion: BCa-patients have more sleep problems, are less depressed and have fewer digestive problems. This strongly suggests complex psycho-vegetative differences between both groups. It remains to be examined if there are further differences i.e. in the circadian melatonin secretion and polysomnography.