Article
Resection of thymomas and thymic carcinomas: a ten year experience
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Published: | September 30, 2010 |
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Background: Thymomas are rare malign tumors of the mediastinum. We want to report our experience with the resection of thymomas at our institution in the years 2000 to 2009.
Methods: In the indicated time period a total of 81 resections were performed. 77 patients who underwent surgery for thymoma were analyzed for survival (overall, recurrence free), Masaoka stage, WHO type, type and completeness of resection, recurrences, the occurrence of paraneoplastic syndromes, other primary malignancies, neoadjuvant and adjuvant therapy.
Results: 13.6% of cases were recurrences of malignant thymomas (referrals from other institutions included). Patients admitted present with Masaoka stage I (29%), stage II (38%), stage III (16%) and stage IV (18%). The following WHO types were found: type A (18%), type AB (5%), type B1 (8%), type B2 (23%), type B3 (14%), type C (18%), mixed type (11%, most frequently B2/B3) and micronodular thymoma (1%). Myasthenia Gravis was present in 31% of cases. In about 88% of cases (incl. recurrences) a complete resection could be reached. In our patient cohort about 13% had a second primary malignancy.
Conclusions: We will discuss the current surgical treatment strategy of thymomas and multimodal approaches for advanced thymomas.
Disclosure: No significant relationships.