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66th Annual Meeting of the German Society of Neurosurgery (DGNC)
Friendship Meeting with the Italian Society of Neurosurgery (SINch)

German Society of Neurosurgery (DGNC)

7 - 10 June 2015, Karlsruhe

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Institutional experience with a novel mechanically detachable flow-diverter (p64) in the treatment of intracranial aneurysms

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  • Annika Kowoll - Institut für Diagnostische und Interventionelle Radiologie, Neuroradiologie und Nuklearmedizin, Universitätsklinikum Knappschaftskrankenhaus Bochum
  • Sebastian Fischer - Institut für Diagnostische und Interventionelle Radiologie, Neuroradiologie und Nuklearmedizin, Universitätsklinikum Knappschaftskrankenhaus Bochum
  • Anushe Weber - Institut für Diagnostische und Interventionelle Radiologie, Neuroradiologie und Nuklearmedizin, Universitätsklinikum Knappschaftskrankenhaus Bochum
  • Christian Löhr - Klinik für Radiologie, Neuroradiologie und Nuklearmedizin, Knappschaftskrankenhaus Recklinghausen
  • Werner Weber - Institut für Diagnostische und Interventionelle Radiologie, Neuroradiologie und Nuklearmedizin, Universitätsklinikum Knappschaftskrankenhaus Bochum

Deutsche Gesellschaft für Neurochirurgie. 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Karlsruhe, 07.-10.06.2015. Düsseldorf: German Medical Science GMS Publishing House; 2015. DocP 138

doi: 10.3205/15dgnc536, urn:nbn:de:0183-15dgnc5361

Published: June 2, 2015

© 2015 Kowoll et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.

Outline

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Objective: The focus of this analysis is to determine ease of deployment, safety and effectiveness of a novel mechanically detachable flow-diverter (p64).

Method: A retrospective analysis was performed of 24 cases in which the p64 was used for the treatment of intracranial aneurysms from February 2013 to September 2014, including all clinical and angiographic data as well as mid-term follow-up (1 - 17 months of treatment).

Results: The median age of the patients was 60 years (range 41 - 78) and 20 (83.3%) were women. The aneurysms were ruptured in 2/24 cases (8.3%); 21 (87.5%) were located within the anterior circulation and the remaining 3 (12.5%) were located in the posterior circulation. For 17 /24 patients, a mid-term follow-up could be performed. Immediate total occlusion was observed in 12/17 (70.6%), and a ‘dog ear’ or subtotal occlusion in 3/17 (17.6%). Complications occurred in 2/24 cases (8.3%), including one case of thrombosis of the parent artery due to failure of antithrombotic medication. In one case the p64 could not be deployed and the parent artery (ICA) had to be occluded.

Conclusions: The flow-diverter p64 offers an effective treatment option for complex and fusiform aneurysms with a low complication rate; initial technical difficulties have been overcome and are furthermore continuously monitored and improved.