gms | German Medical Science

66th Annual Meeting of the German Society of Neurosurgery (DGNC)
Friendship Meeting with the Italian Society of Neurosurgery (SINch)

German Society of Neurosurgery (DGNC)

7 - 10 June 2015, Karlsruhe

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Clinical and radiological outcome following anterior cervical discectomy and fusion with stand-alone PEEK cages with or without osteogenic filling substance – a retrospective matched-pair analysis

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  • Ehab Shiban - Neurochirurgische Klinik, Technische Universität München
  • Johann Kogler - Neurochirurgische Klinik, Technische Universität München
  • Moriz Nies - Neurochirurgische Klinik, Technische Universität München
  • Jens Lehmberg - Neurochirurgische Klinik, Technische Universität München
  • Bernhard Meyer - Neurochirurgische Klinik, Technische Universität München

Deutsche Gesellschaft für Neurochirurgie. 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Karlsruhe, 07.-10.06.2015. Düsseldorf: German Medical Science GMS Publishing House; 2015. DocP 073

doi: 10.3205/15dgnc471, urn:nbn:de:0183-15dgnc4718

Published: June 2, 2015

© 2015 Shiban et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.

Outline

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Objective: To evaluate the influence of demineralized bone matrix (DBM) on long-term results after anterior cervical discectomy and fusion (ACDF) with stand-alone PEEK cages.

Method: A retrospective age-, gender-, symptoms- and level-matched pair analysis was performed on 45 pairs of patients who underwent anterior cervical discectomy and fusion (ACDF) with stand-alone PEEK cages with a minimum follow-up of 12 months. In the study group, DBM was used as an osteogenic filling substance. Radiographic follow-up included static and flexion/extension radiographs. Changes in the operated segments were measured and compared to radiographs directly after surgery. Clinical outcome was evaluated by a physical exam and the EuroQOL questionnaire (EQ-5D).

Results: Fusion rate in the study group was 83% and 86% the control group. Subsidence rate in the study group was 33% and 22% in the control group. Cervical alignment improved in 2% and 11%, worsened in 20% and 11% and remained same in 71% and 78% in the study and control group, respectively. VAS Overall Health increased from 46 ± 23 to 74 ± 21 in the study group and from 37 ± 22 to 73 ± 23 in the control group.

Conclusions: Application of DBM for ACDF with stand-alone PEEK cages has no significant influence on radiological or clinical outcome.