gms | German Medical Science

62nd Annual Meeting of the German Society of Neurosurgery (DGNC)
Joint Meeting with the Polish Society of Neurosurgeons (PNCH)

German Society of Neurosurgery (DGNC)

7 - 11 May 2011, Hamburg

A correlation analysis on the size of ruptured cerebral aneurysms and the diameter of related parent arteries

Meeting Abstract

  • N. Etminan - Neurochirurgische Klinik, Heinrich-Heine-Universität, Düsseldorf
  • K. Beseoglu - Neurochirurgische Klinik, Heinrich-Heine-Universität, Düsseldorf
  • Ü. Kozan - Neurochirurgische Klinik, Heinrich-Heine-Universität, Düsseldorf
  • H.J. Steiger - Neurochirurgische Klinik, Heinrich-Heine-Universität, Düsseldorf
  • D. Hänggi - Neurochirurgische Klinik, Heinrich-Heine-Universität, Düsseldorf

Deutsche Gesellschaft für Neurochirurgie. Polnische Gesellschaft für Neurochirurgen. 62. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgen (PNCH). Hamburg, 07.-11.05.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. DocP 013

doi: 10.3205/11dgnc234, urn:nbn:de:0183-11dgnc2346

Published: April 28, 2011

© 2011 Etminan et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Objective: Previous studies based on theoretical flow dynamic measurements reported a potential correlation of the size of related parent vessels to the ruptured aneurysm itself. The goal of the present study was to analyze this correlation in a large patient cohort.

Methods: Retrospectively, patients were included in the analysis who met the following criteria: 1) Aneurysmal subarachnoid hemorrhage, and 2) Accurate 3-dimensional (3D) digital subtraction angiography. Aneurysm aspect ratios (maximum diameter and neck size) as well as the exact parent vessel calibers were measured by two independent investigators (NE, ÜK). Linear regression models were calculated using SPSS.

Results: 220 patients were included in the present study. Median aneurysm size was 6.59 mm, with 74.5% of the aneurysms smaller than 7mm. The majority of the aneurysms were localized at the anterior communicating artery (ACOM: 36.4%), middle cerebral artery (MCA: 20.9%), posterior communicating artery (PCOM: 14.1%) and basilar artery (BA: 10.9%). Despite significant differences between the mean aneurysm sizes among the ACOM, MCA and BA (p < 0.001), there was no correlation between the mean aneurysm size and parent vessel diameter for ACOM, MCA and BA (R2, linear = 0.036, 0.003, 0.222, respectively). However, there was a moderate correlation between aneurysm diameter and neck width (R2, linear = 0.23).

Conclusions: The data in the present analysis, derived from a large clinical cohort, do not support the assumption of a significant relation between the size of related parent vessels to the ruptured aneurysm itself. This underlines the growing evidence that alternative factors additional to flow dynamics could be responsible for cerebral aneurysm rupture.