gms | German Medical Science

83. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

16.05. - 20.05.2012, Mainz

Multidisciplinary management of congenital neuroblastoma in infants

Meeting Abstract

  • Miklos Csanady - HNO, Uni.-Klinik Szeged, Ungarn, Szeged, Ungarn
  • Valeria Majoros - Dept. of Anesthesiology and Intensive Care, University of Szeged, Szeged, Hungary
  • Gabor Vass - Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Szeged, Hungary
  • Katalin Bartyik - Dept. of Pediatry and Center of Pediatric Healthcare, University of Szeged, Szeged, Hungary
  • Jeno Czigner - Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Szeged, Hungary

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 83. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Mainz, 16.-20.05.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12hnod147

doi: 10.3205/12hnod147, urn:nbn:de:0183-12hnod1475

Veröffentlicht: 4. April 2012

© 2012 Csanady et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Introduction: Authors present management of a rare malignant tumour of the neck: diagnostic, surgical and oncological treatment of neuroblastoma in 2 infants.

Methods: In both 6 months old infants a right neck lump developed – multiple tumour and lymph nodes. On the basis of clinical findings, quick progression of the tumour and MRI scans neck malignancy was suspected and surgical resection of the tumour was indicated (neck dissection). Pathological findings established neuroblastoma in both infants, so chemotherapy was started at the Department of Pediatry (SIOP, neuroblastoma protocol).

Results: In the first case a metastatic lesion was observed on the left neck 2 months later as well. Neck dissection (mRND) was performed on the left too and chemotharapy was administered. There is no recurerrence since 13 months.

In the other infant resection of the right neck malignancy was performed (mRND) and chemotherapy was given. Since 12 months there is no sign of recurrence. This infant was also treated with chronic severe dysphagia, muscular hypotony and somato-mental disorder, PEG was inserted for feeding.

Their postoperative MRI showed no recurrence.

Conclusions: Prognosis of the neck neuroblastoma in infants (under age of 1 year) after early detection and treatment is good, but age, pathological finding and genetic (N-myc expression) have an impact on it.