gms | German Medical Science

80. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

20.05. - 24.05.2009, Rostock

Gigant cell lesions of the nasal cavity and sinuses

Meeting Abstract

  • corresponding author Wieslaw Golabek - Otolaryngology Dept., Lublin, Poland
  • Kamal Morshed - Otolaryngology Dept., Lublin, Poland
  • Agnieszka Fronczek - Pathology Dept., Lublin, Poland
  • Ewa Golabek - Radiology Dept., Lublin, Poland

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 80. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Rostock, 20.-24.05.2009. Düsseldorf: German Medical Science GMS Publishing House; 2009. Doc09hnod340

DOI: 10.3205/09hnod340, URN: urn:nbn:de:0183-09hnod3404

Veröffentlicht: 17. April 2009

© 2009 Golabek et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Giant cell tumours (osteoclastoma) are very uncommon neoplasms in the facial skeleton. Their usual clinical presentation is in the long bones. The differential diagnosis of giant cell tumour (GCT) in the facial skeleton includes giant cell granuloma (GCG), brown tumour, nonossifying fibroma, chondroblastoma and odontogenic cyst. It can be very difficult to differentiate histologically three lesions: giant cell tumour, giant cell granuloma and brown tumour related to hyperparathyroidism

One case of GCT and five cases of GCG are presented. Four men and one woman aged 14–68 years had GCG that occupied the maxillary sinus and nasal cavity. Clinical symptoms included swelling of the cheek, nasal obstruction and facial pain. CT well demonstrated extension of the lesion and erosion of the alveolar process and sinus walls. The lesions were removed using sublabial approach with disease free 4–15 years follow up.

A 16 years old boy presented with unilateral blindness, headache and biopsy result: giant cell tumour. Imaging radiography revealed involvement of the sphenoid sinus, orbit apex and middle cranial cavity bilaterally. We removed the tumour subtotally using subcranial approach. A year later he was operated again in another institution and this resulted with bilateral blindness and temporary haemiplegia.

Concluding, CT and MRI well demonstrate giant cell lesions and the goal of surgical treatment is radical removal. This might not always be possible when the giant cell tumour invades the skull base.