gms | German Medical Science

14. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie

Gesellschaft für Arzneimittelforschung und Arzneimittelepidemiologie

15.11. - 16.11.2007, Frankfurt am Main

Secondary medical prevention of acute coronary syndromes: a six-months follow-up study

Meeting Abstract

Suche in Medline nach

  • corresponding author S. Loeffert - ZVFK - Center for Health Services Research Cologne, University of Cologne
  • S. Thuem - Devision of Medical Sociology, Institute and Policlinic for Occupational and Social Medicine of the University of Cologne
  • H. Pfaff - ZVFK - Center for Health Services Research Cologne, University of Cologne

Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie e.V. (GAA). 14. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie. Frankfurt am Main, 15.-16.11.2007. Düsseldorf: German Medical Science GMS Publishing House; 2007. Doc07gaa27

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/gaa2007/07gaa27.shtml

Veröffentlicht: 12. November 2007

© 2007 Loeffert et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Context: Modifications in pharmaceutical treatment can occur at various extent and different stages in the course of continued medical care.

Aim of the study: This study examines changes in medication with therapeutic guideline recommendation of patients with acute coronary syndromes over a six-months period.

Material and method: A health diary covering health condition and medication was filled in on a weekly basis during a six-months period by n = 104 patients (73% male, average age = 62 years) initially hospitalised with acute coronary syndromes in the Cologne area (Germany). Changes in medication between hospital discharge, week 2, week 12 and week 24 were determined.

Results: 66% of patients showed 5 different diseases (ICD-10 diagnoses) at hospital discharge (Minimum = 1, Maximum = 9). Patients took on average 6 drugs per day within the observation period (Minimum at week 24 = 0, Maximum at week 24 = 14). Few changes in medication were observed in a population based approach: e.g. 56% of patients received clopidogrel at hospital discharge, while 43% obtained it at week 24. 85% of patients received acetylsalicylic acid at hospital discharge and 78% at week 24. Variation in prescription were determined on the individual level: e.g. 64% of those patients that received clopidogrel at hospital discharge continuously obtained it until week 24 and 86% of patients that obtained acetylsalicylic acid at hospital discharge still obtained it at week 24.

Conclusion: Many patients were treated with polypharmacy due to the relative high percentage of patients suffering from multimorbidity. Though few changes in medication were observed during continued medical care in a population based approach over a six-months period. However, broader variation in medication was determined on the individual level. Despite the variation in prescription in the individual therapy, the overall prescription behaviour of physicians showed a good implementation of therapeutic guidelines.