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61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010
Joint Meeting mit der Brasilianischen Gesellschaft für Neurochirurgie am 20. September 2010

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

21. - 25.09.2010, Mannheim

Visual impairment and proptosis due to bilateral sphenoorbital intraosseous meningiomas: a therapeutic challenge

Meeting Abstract

Suche in Medline nach

  • Goetz Luetjens - Neurochirurgische Klinik, Medizinische Hochschule Hannover, Germany
  • Joachim K. Krauss - Neurochirurgische Klinik, Medizinische Hochschule Hannover, Germany
  • Makoto Nakamura - Neurochirurgische Klinik, Medizinische Hochschule Hannover, Germany

Deutsche Gesellschaft für Neurochirurgie. 61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010. Mannheim, 21.-25.09.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. DocP1728

doi: 10.3205/10dgnc199, urn:nbn:de:0183-10dgnc1999

Veröffentlicht: 16. September 2010

© 2010 Luetjens et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen ( Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.



Objective: Bilateral intraosseous meningiomas of the sphenoid wing infiltrating both the orbits and the frontotemporal skull base with bilateral proptosis and visual impairment are extremely uncommon. Thus far, no treatment algorithms have been suggested for this entity. We report on the surgical management of three patients with bilateral hyperostotic sphenoorbital menigiomas.

Methods: All 3 patients underwent a pterional approach for surgical resection. Surgery was performed in two stages, primarily treating the most affected side. Treatment consisted of microsurgical resection of the infiltrated sphenoid wing and orbital walls, intraorbital tumor removal and optic nerve decompression. Orbital wall reconstruction was performed using titanium mesh allografts. Radiation therapy was administered in 1 patient with residual tumor infiltration of the cavernous sinus.

Results: Our series includes 2 women (51 and 68 years old) suffering from simultaneous progressive bilateral loss of vision and proptosis and 1 woman (69 years old), who developed contralateral disease after surgical resection of an intraosseous sphenoorbital meningioma 16 years earlier. After optic nerve decompression, vision improved in 2 cases after surgery. Initial visual deterioration was observed in 1 case but improved on long-term follow-up. The degree of proptosis was reduced in all treated eyes. There was no perioperative mortality.

Conclusions: In bilateral intraosseous sphenoorbital meningiomas, we propose staged surgery when clinical and radiological progression is observed. Although radical tumor resection is practically impossible in such extensive lesions, subtotal tumor resection with the aim of optic nerve decompression and subsequent orbital reconstruction provides satisfactory results. The most affected eye, which is not necessarily the eye with the most extensive tumor growth, should be treated first. In case of additional cavernous sinus infiltration, focal radiation therapy can be considered.