Artikel
Fever does not raise intracranial pressure
Fieber verursacht keinen erhöhten Hirndruck
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Autoren
Veröffentlicht: | 4. Mai 2005 |
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Gliederung
Text
Objective
Clinical observations led to the believe that fever and high brain temperature may elevate ICP. The presented data demonstrate with >40.000 single measurements that brain/body temperature and ICP values do not correlate.
Methods
In 32 consecutive neurosurgical patients brain temp., core temp. and ICP were recorded continuously with a 5 min interval. Brain temperature sensor: combined ICP/temperature probe (Raumedic®), Core temperature sensor: urinary catheter with temperature probe (Rüsch®). Combined sampling error: <0.13 °C. The ICP/temperature probes were implanted 3 cm deep into the frontal parenchyma. Design: prospective, non randomized, open labeled.
Results
No correlation between ICP and brain temperature could be observed (re=0.07, p<0.01). The mean brain temperature is 0.3°C higher than the core temperature, p<0.001. Single patients with meningitis/encephalitis displayed an early increase of the brain temperature without elevated body temperature.
Conclusions
Raise and fall of ICP is not influenced by the body/brain temperature. The clinical meaning of this observation is that antipyretic therapy will not contribute significantly to ICP management.