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78th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

16.05. - 20.05.2007, Munich

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Functional Endoscopic sinus surgery and Fluticasone propionate aqueous nasal spray in the treatment of nasal polyposis

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  • corresponding author Merab Khvadagiani - HNO-KLinik der Medizinischen Universitaet, Tbilisi, Georgien
  • Ekaterine Khvadagiani - HNO-Klinik Medizinischer Universitaet, Tbilissi, Georgien
  • Pimen Kurashvili - HNO-Klinik Medizinischer Universitaet, Tbilissi, Georgien
  • Gela Chwadagiani - HNO-Klinik Medizinischer Universitaet, Tbilissi, Georgien

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 78. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.. München, 16.-20.05.2007. Düsseldorf: German Medical Science GMS Publishing House; 2007. Doc07hnod397

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/hnod2007/07hnod397.shtml

Published: April 24, 2007

© 2007 Khvadagiani et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Introduction: The managment of nasal polyposis (NP) is undoubtedly a controversial subject. The aim of the present study is to compare the improvement of symptoms associated to NP 1) After Functional Endoscopic sinus surgery (FESS) and 2) After topical nasal steroid therapy 3 months before and after FESS.

Materials and Methods: 57 patients with clinically diagnosed NP participated in this investigation. In all patients FESS (Polypectomy, uncinectomy, partial antero-interior middle turbinectomy, Antrostomy and complete ethmoidectomy) was performed under control with a 0°, 30° and 70° endoscopes.

Symptoms were recorded on Visual analogs scales before and after three months later the day of surgery (27 patients) and after topical Fluticasone propionate nasal spray (FPNS) therapy (FPNS 200 mg. twice daily) for at least 3 months before and after FESS (30 patients).

Results: Nasal obstruction was major complaint at entry in the study. Following local steroid course the obstruction score improved signficantly. POst-operative normalisation of nasal function was obtinaid in 64% of first group patients and 70% of second group. Following surgery and local steorid therapy nasal symptoms (nasal obstruction, anosmia or hyposmia, anterior and/or posterior rhinorrhea, sneezing and itching and facial pain) were improved more signficantly in second group patients, than in first group (p› 0,05).

Conclusion: These data showed that functional Endoscopic sinus surgery is effective for patients with nasal polyposis.

FESS is more effective when the patients recieve local steroid therapy, FPNS 200 mg. twice daily, three months before and after surgery.