gms | German Medical Science

104th DOG Annual Meeting

21. - 24.09.2006, Berlin

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Clinical effects of laser thermokeratoplasty in rabbits' eyes

Meeting Abstract

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  • V. Y. Usov - The Filatov Institute of Eye Diseases and Tissue Therapy, Odessa
  • L. A. Linnik - The Filatov Institute of Eye Diseases and Tissue Therapy, Odessa
  • E. V. Maltsev - The Filatov Institute of Eye Diseases and Tissue Therapy, Odessa
  • V. S. Repiah - The Filatov Institute of Eye Diseases and Tissue Therapy, Odessa

Deutsche Ophthalmologische Gesellschaft e.V.. 104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft (DOG). Berlin, 21.-24.09.2006. Düsseldorf, Köln: German Medical Science; 2006. Doc06dogP089

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dog2006/06dog611.shtml

Published: September 18, 2006

© 2006 Usov et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Objective

A method of change of cornea curvature by thermal influence (so-called refraction thermokeratocoagulation) is known since long. A new stage of development of refraction surgery is related to introduction of laser technologies. To study the features of change of refraction of rabbit eyes in case of coagulation influence of diod-laser on the cornea of experimental animals in vivo.

Methods

A total of 13 adult rabbits were used. All procedures were performed with contact diod-laser energy (1.06) 250mJ focusing device. Animals were anesthetized with intramuscular ketamine HCL (100mg/kg) and topical Sol.Dicaini 1%.Two symmetric rings of eight laser coagulation spots per ring at 5 and 7 mm centered on the visual axis were applied.

Results

The symptoms of irritation of eyes at all rabbits to the 5-7 days calmed down. Complete epitelization came within 4-5 days. As a result of operation a reliable (p<0.05) change of refraction is attained statistically. The difference between the attained refraction result of operation and preoperative level of clinical refraction of eyes of experimental animals averaged 2.28±0.75D (from 1 to 3.25 D). After 12 months the difference between the refraction effect of operation and preoperative level of clinical refraction averaged, 1.45±0.76 D.

Conclusions

The conducted researches show the possibility of application in the clinic of diod-laser (1.06) thermokeratoplasty for correction of hyperopia of weak degree.