gms | German Medical Science

The electrocardiological investigation could not prognosticate the exact decrease of systolic function of the heart not yet in case of Q-wave myocardial infarction (QMI), either. Quantitative body surface potential mapping (BSPM) parameters (the ratio /Max/Min/ and time-difference /Timeshift/ of the highest maximum and deepest minimum potential) show significant relationship with the location of QMI (with best diagnostic value in case of anterior necrosis). In present study we investigated the relationship between BSPM parameters (whose are indicating anterior electrical potential loss) and impaired left ventricular systolic function in non ST elevation acute coronary syndrome (NSTE-ACS).

Methods: 175 NSTE-ACS cases (123 men, 31-78 years, average: 62) in stable state (when the ECG did not show the signs of NSTE-ACS) and 33 healthy subjects (15 men, 23-72 years, average: 48,8) were investigated by BSPM (63 lead Montreal system). Max/Min and Timeshift were calculated from the isopotential maps during the depolarization. Ejection fraction (EF) was judged from transthoracic ultrasound echocardiography.

Results: concerned cases with Max/Min <0.8 and/or Timeshift <-4ms (45 cases), the averaged EF was 42.9¡À8.3%. When these parameters were not fulfilled (121 cases), the EF was 57.8¡À7.5%. The EF was 61.4¡À6.1% in the normal group. The groups has differed form each others significantly (two samples Student t-probe, p<0,0001). In prognosis of EF¡Ü48%, the diagnostic value of these parameters was: sensitivity: 73.1%, specificity: 93.9%, positive predictive value: 80.9%, and negative predictive value: 90.8%, respectively.

Conclusion: the investigated BSPM parameters can indicate impaired systolic function in NSTE-ACS that is an electrocardiological investigation can give information about the mechanical function of the heart.