Artikel
Reproducibility of office-, home- and 24-hour ambulatory blood pressure measurement
Reproduzierbarkeit von drei nicht invasiven Blutdruckmessverfahren
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Veröffentlicht: | 8. August 2006 |
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Aims: To compare the reproducibility of three different blood pressure (BP) measurement methods:1) office BP, 2) home BP (Omron wrist device 637 IT with position sensor), 24-hour ambulatory blood pressure measurement (24-h ABPM) (Cardiotens 04 Meditech, Hun).
Methods: Conventional, sphygmomanometric office BP (two consecutive measurements) was performed at study day one and seven, 24-h ABPM was performed at study day seven and fourteen, home BP (two consecutive measurements in the morning and evening) was performed consecutively between study days one and seven and between study days eight and fourteen in 69 hypertensive and 28 normotensive subjects. Subjects were instructed how to use the oscillometric Omron wrist device for home blood pressure measurement.
Results: Mean systolic/diastolic (mm Hg) BP values were 148±24/92±13 and 144±21/90±12 for office BP at study day one and seven respectively, 135±16/84±12 and 134±16/83±12 for home BP in the first and second week respectively, 131±15/79±11 and 133±16/80±11 for 24-h ABPM at day seven and fourteen respectively.
The reproducibility of BP measurement was analysed by comparing the within subject standard deviations (SD) between the respective BP measurements. Mean within subject SD (confidence interval) for office-, home- and 24-h ABP were for systolic BP: 8.10 [7.10-9.43], 3.81[3.34-4.44] and 7.87 [6.90-9.17], for diastolic BP 4.76 [ 4.18-5.54], 2.77 [2.43-3.22] and 4.09 [3.59-4.77].
The reproducibility of systolic and diastolic home BP was significantly higher than the reproducibility of office BP (p=0.0005 systolic BP, and p=0.001 diastolic BP) and the reproducibility of 24-h ABPM (P=0.0007 systolic BP, p=0.127 diastolic BP). The reproducibility of systolic and diastolic office and 24-h ABPM was not significantly different (p=0.8 systolic, p=0.1 diastolic).
Conclusions: The short time reproducibility of home BP measurement with the Omron 637 wrist device was superior to the reproducibility of office BP and 24- ABPM measurement. This finding is important for pharmacological studies as well as clinical use of home BP.