gms | German Medical Science

76. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

04.05. - 08.05.2005, Erfurt

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Our preliminary findings with fractionated stereotactic radiotherapy on acoustic neuroma

Meeting Abstract

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  • corresponding author Jan Rudolf - Department of Otolaryngology, Head and Neck Surgery, Medical School, Otto-von-Guericke-University Magdeburg, Güstrow, Germany
  • Claudia Pambor - Clinic for Radiotherapy, Medical School, Otto-von-Guericke-University Magdeburg, Germany
  • Bernd Freigang - Department of Otolaryngology, Head and Neck Surgery, Medical School, Otto-von-Guericke-University Magdeburg, Germany
  • Günther Gademann - Clinic for Radiotherapy, Medical School, Otto-von-Guericke-University Magdeburg, Germany
  • Hellmut von Specht - Dept. of Experimental Audiology and Medical Physics, Medical School, Otto-von-Guericke-University Magdeburg, Germany

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 76. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.. Erfurt, 04.-08.05.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc05hno495

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/hno2005/05hno135.shtml

Veröffentlicht: 22. September 2005

© 2005 Rudolf et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

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Aims: When treating patients with acoustic neuroma on one side with radiotherapy the side effects could be reduced by using a fractionated X-ray application rather than irradiation on one side. The aim of this study is to carry out continuous audiological and neurootological monitoring accompanying the treatment to record epiphenomena.

Methods: Since January 2000 a total of 48 patients have been examined before and after hypofractionated (5 x 4 Gy, every 2 days) or normofractionated treatment (30 x 1.8 Gy). Apart from subjective audiometry the range of tests included brain stem audiometry (ABR = auditory brain stem response), the blink reflex and vestibular diagnosis. The findings were collected at three or six month intervals and the data from the MRT was compared.

Results: The test results for audiometry, the ABR and vestibular diagnosis turned out to be very different but they showed a correlation to morphological conversion processes in the MRT. While the changes were sub-clinical for the facial nerve, some patients suffered a significant deterioration in initial audiological and vestibular findings even after quite long time intervals (up to 9 months).

Conclusions: The results obtained show the necessity for long term monitoring.