Artikel
Cerebral autoregulation remains intact during AVM resection
Der zerebrale Autoregulationsmechanismus während AVM-Resektion ist intakt
Suche in Medline nach
Autoren
Veröffentlicht: | 11. April 2007 |
---|
Gliederung
Text
Objective: To test the hypothesis that function of cerebral autoregulation in AVM patients undergoing resective surgery differs to the one observed in nonvascular patients.
Methods: Dynamic autoregulation (AR) via correlation coefficient index method (CCI) was assessed before and after resection in n=12 patients with small/medium-sized AVM and transsylvian dissection in n=15 patients with nonvascular lesions (=controls). MAP, CBF (thermal dilution method), and routine Intraoperative physiological parameters were continuously measured. All data were pooled according to groups and times, and compared via ANOVA (P<0.05) and post-hoc Wilcoxon correction for multiple comparisons. All data (given below as means ± SD) were collected in the context of a prospective study.
Results: CCI did not show any significant within-group or between-group differences regarding the controls (control pre: 0.06±0.4, post: -0.04±0.5) and AVM-group (pre: 0.04±0.4, post: 0.04±0.5)), respectively.
Conclusions: Dynamic autoregulation results indicate that the status of autoregulation is not altered in patients with uncomplicated small or medium AVM compared to non-AVM conditions. During resective surgery, autoregulation remains intact in AVM patients.