Figure 1: Variation in TCERG1L (rs893507) association with cisplatin-induced hearing loss is genome-wide significant by combined analysis in three independent patient cohorts (I2=8.1). The combined analysis showed that patients who carry the C allele increased the odds of cisplatin-induced hearing loss with 3.11 (95% CI 2.2–4.5) compared to patients who carry the T allele. Abbreviations: OR=odds ratio; PCL=PanCareLIFE.