Figure 3: Test procedure for the swift modified alkali resistance test (SMART) as presently practiced by the “Task force on Assessment and Evaluation of Irritant Skin Damages” of the ABD
Test site: medial forearm, ventral. The same procedure is performed for the differential irritation test (DIT), when the SMART is carried out in parallel on the back of the hand corresponding to chirality and the contralateral forearm. TEWL = transepidermal waterloss. Clinical and biophysical readings are to be conducted 10 min after the second provocation phase.