Figure 36: Best clinical condition and MRI findings up to 2.5 years after irradiation further marginal tumor regression. 4 years later, again significant tumor growth to 14.2 cm³. Meanwhile, the patient had to undergo dialysis because of renal failure. She strictly refused surgery. Upon her urgent wish, again SRT with 22x1.8 Gy was started that had to be interrupted after the 16th fraction because of a fall with bilateral fractures of the ischium and the pubic bones and intensive care that was necessary because of metabolic imbalance. The patient dies of multiorgan failure.