Figure 4: Histamine-dose-efficacy-curve after allergen-stimulation of human basophile granulocytes in vitro. The maximum of histamine release (displayed in percentage of total histamine-content (100%)) behaves independently of the cell sensitivity (indicated as allergen-concentration e.g. for 30% histamine- release (Ag30)). The analysis is aggravated by the individual variability (differences of multiple decimal power).