gms | German Medical Science

International Conference on SARS - one year after the (first) outbreak

08. - 11.05.2004, Lübeck

Data analysis to discover molecular evolution of the SARS-CoV


Search Medline for

  • corresponding author presenting/speaker Pei Hao - Pei Hao, Shanghai, China
  • Weizhong He - Pei Hao, Shanghai, China
  • Yixue Li - Pei Hao, Shanghai, China

International Conference on SARS - one year after the (first) outbreak. Lübeck, 08.-11.05.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04sarsP4.02

The electronic version of this article is the complete one and can be found online at:

Published: May 26, 2004

© 2004 Hao et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



This work helped the Chinese Severe Acute Respiratory Syndrome (SARS) molecular epidemiology consortium analyze the molecular evolution of the SARS-causing coronavirus (SARS-CoV) during the course of the first SARS epidemic in China. We are introducing the method that is used to determine the segregation of SARS-CoV genotypes into major groups in details. In addition, we further characterize the molecular evolutionary properties of individual function units. To simplify this work, we build a workflow based on Knowledge Discovery Environment (KDE).


E. J. Snijder et al., J. Mol. Biol. 331, 991 (2003)