gms | German Medical Science

25th Annual Meeting of the German Retina Society

German Retina Society

01.06. - 02.06.2012, Münster

Choroidal neovascularization membranes (CNV) in patients without signs of age related macular degeneration (nonAMD): Presentation of CNV structures with availble equipment is possible in a non-invasive way

Meeting Abstract

  • Werner Inhoffen - Universitäts-Augenklinik Tübingen
  • C. Kernstock - Universitäts-Augenklinik Tübingen
  • K.U. Bartz-Schmidt - Universitäts-Augenklinik Tübingen

German Retina Society. 25th Annual Conference of the German Retina Society. Münster, 01.-02.06.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12rg45

doi: 10.3205/12rg45, urn:nbn:de:0183-12rg453

This is the translated version of the article.
The original version can be found at:

Published: May 30, 2012

© 2012 Inhoffen et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Purpose: To explore the possibility of non-invasive presentation of nonAMD-CNV with commercially available optical coherence tomography (FD-OCT).

Methods: Using Spectralis OCT ( Heidelberg Engineering, Dossenheim) with parallel B-scans (lateral resolution 11 µm) and C-scan presentation, we examined patients with non-AMD CNV: 4 patients with myopic CNV (mCNV), 4 patients with idiopathic CNV (iCNV), 5 patients with CNV and angoid streaks (AS-CNV), 3 patients with CNV and bilteral, juxtafoveolar teleangiectasis (BJT-CNV) and 3 patients with chronic central serous chorioretinopathy (cCSC). Evaluation was further supported by angiography (FLA), funduscopy and B-scan images of the same OCT scans.

Results: A)mCNV: Despite of posterior staphyloma, CNV pattern similar to FLA results appeared , more obvious in new CNV. B) iCNV: Although the lesions were prominent, CNV pattern were detectable inside the lateral pigment epithelial borders. C) AS-CNV: Above Bruch’s membrane CNV pattern exceeding those expected by funduscopy were present. D) BJT-CNV: Even old, inactive CNV were seen similar to those in FLA before. In contrast, connection areas of retinal vessels with the choroid were only detectable by comparing the C-scan image with funduscopy. E) cCSC: Pigment epithelial detachments showed CNV vessels or only dense pigment with small retinal vessels (no CNV) in accordance with FLA findings.

Conclusions: Although the 11 µm C-scan examination method using Spectralis OCT is time consuming, it is a simple and non-invasive way to observe structure, area and distance to Bruch’s membrane of active or inactive CNV in nonAMD.