gms | German Medical Science

24th Annual Meeting of the German Retina Society

German Retina Society

17.06. - 18.06.2011, Aachen

Pigment epithelial tears in association with intravtreal ranibizumab therapy of pigment epitheial detachment in AMD: Long term visual outcome with OCT based reinjection criteria

Meeting Abstract

  • Matthias Gutfleisch - Augenabteilung, St. Franziskus-Hospital Münster
  • B. Heimes - Augenabteilung, St. Franziskus-Hospital Münster
  • M. Dietzel - Augenabteilung, St. Franziskus-Hospital Münster
  • G. Spital - Augenabteilung, St. Franziskus-Hospital Münster
  • A. Lommatzsch - Augenabteilung, St. Franziskus-Hospital Münster
  • D. Pauleikhoff - Augenabteilung, St. Franziskus-Hospital Münster

German Retina Society. 24th Annual Conference of the German Retina Society. Aachen, 17.-18.06.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. Doc11rg32

doi: 10.3205/11rg32, urn:nbn:de:0183-11rg329

This is the English version of the article.
The German version can be found at: http://www.egms.de/de/meetings/rg2011/11rg32.shtml

Published: June 15, 2011

© 2011 Gutfleisch et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

Purpose: Retinal pigment epithelium (RPE) tears may develop as a complication after anti-VEGF-treatment for pigment epithelial detachments (PED) in exudative age-related macular degeneration (AMD). This retrospective study analyses best-corrected visual acuity (BCVA) with OCT based reinjection criteria after RPE tears.

Methods: 47 patients with RPE tears during ranibizumab therapy for progressive PED in AMD were included in this monocenter, retrospecitve study. We analyzed BCVA and quantity of injections. Mean follow-up was 81 weeks.

Results: BCVA did not deteriorated after RPE tear and during follow-up significantly (p<0.181). However, if the number of injections within the first year after RIP was less than 3 BCVA deteriorated significantly compared to patients with 3–6 or more injections (p<0.001)

Discussion: With OCT-based reinjection criteria and a long term, regular examination mean BCVA was better compared to previous course of BCVA in the long term. Accordant change of retreatment strategy after RPE tear seams to be reasonable.