Article
Value of microperimetry in patients with retinal vein occlusion
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Authors
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Sibylle Winterhalter
- Charité, University School of Medicine Berlin, University Eye Clinic, Campus Virchow Clinic and Campus Benjamin Franklin, Berlin
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A. Lux
- University Eye Clinic Düsseldorf
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K. Huber
- University Eye Clinic Düsseldorf
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C. Scholz
- University Eye Clinic Düsseldorf
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V. Kakkassery
- Charité, University School of Medicine Berlin, University Eye Clinic, Campus Virchow Clinic and Campus Benjamin Franklin, Berlin
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F.M.A. Heußen
- Charité, University School of Medicine Berlin, University Eye Clinic, Campus Virchow Clinic and Campus Benjamin Franklin, Berlin
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A.M. Joussen
- Charité, University School of Medicine Berlin, University Eye Clinic, Campus Virchow Clinic and Campus Benjamin Franklin, Berlin
| Published: | September 21, 2010 |
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Outline
Text
Background: In patients with retinal vein occlusion subjective changes in vision frequently cannot be confirmed by objective measurements (distance and near visual acuity, OCT).
Methods: In a prospective case series of 13 patients with central or branch retinal vein occlusion the value of microperimetry was tested in comparison to distance and near visual acuity and OCT. Patients with macular edema were treated with intravitreal bevacizumab injections and patients with peripheral ischemia with photocoagulation. Follow-up was performed every 6 weeks, 6–14 months. Microperimetry was divided into 3 subgroupes: 1. all 40 points, 2. central 8 points, 3. in branch vein occlusion involved retinal sector.
Results: Four patients with central and 9 patients with branch vein occlusion were included into the study. Average macular edema was 718 µm in patients with central and 337 µm in patients with branch vein occlusion at baseline. Average macular edema was reduced to 385 µm (+/–165.33) at last follow-up. Seven patients were treated with bevacizumab injections and 4 patients with photocoagulation. Average distance visual acuity remained constant (0.32+/–0.31). Average near visual acuity improved in 50% (0.37+/–0.42) without statistical significance (p=0.597). Mean light sensitivity improved statistical significant: The 40 points group improved in 50% (p=0.015) to 10,55+/–4,91 dB, the central 8 points group improved in 70% (0.041) to 7,78+/–6,5 dB and the sector group in 87% (0.014) to 9,21+/–5,51 dB.
Conclusion: Microperimetry was superior in demonstrating changes in vision than distance and near visual acuity in patients with retinal vein occlusion.
