gms | German Medical Science

23rd Annual Meeting of the German Retina Society

German Retina Society

24.09. - 25.09.2010, Freiburg

Two cases of adult retinoblastoma treated by radiotherapy

Meeting Abstract

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  • Christina L. M. Weiß - University Eye Clinic Essen
  • C. Jurklies - University Eye Clinic Essen
  • N. Bornfeld - University Eye Clinic Essen

German Retina Society. 23rd Annual Conference of the German Retina Society. Freiburg i. Br., 24.-25.09.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. Doc10rg36

doi: 10.3205/10rg36, urn:nbn:de:0183-10rg360

This is the translated version of the article.
The original version can be found at:

Published: September 21, 2010

© 2010 Weiß et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Background: Description of two clinical courses their therapy and histopathology. We treated in our clinic two male patients with late-onset disease of retinoblastoma during adulthood with radiotherapy. In one of the cases a retinom without progress was previously diagnosed at least five years prior first presentation at our clinic.

Methods: Retrospective case report (two patients).

Results: In both cases the unilateral effected eye was treated by radiotherapy. In one of the cases with external beam radiation, in the other one we preformed gamma-knife radiation. Tumour regression was seen in both eyes, but uncontrolled tumour growth led to enucleation of both eyes during one year after treatment. The histopathology showed in both cases an undifferentiated retinoblastoma.

Conclusion: These two cases show that retinoblastoma should always be included as a differential diagnoses even in adulthood. Although the precondition was good to achieve tumour control by radiation therapy, in the end we saw unexpected tumour growth with the loss of both effected eyes.