Article
Endoresection of large uveal melanoms after pretreatment by single-dose stereotactic convergence irradiation with gamma-knife and adjuvant brachytherapy – long term results
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Published: | September 21, 2010 |
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Background: The therapy of large uveal melanomas remains a challeging task in ophthalmology. The aim of this retrospective study was to compare the results of the brachytherapy with ruthenium-iodone and the surgical removal after gamma-knife and adjuvant brachytherapie.
Methods: We compared the longterm results of large uveal melanomas after gamma-knife, endoresection and adjuvant brachytherapy to a treatment with iodine-ruthenium alone. Specical focus was laid on visual acuity, tumor control and the rate of secondray enucleation.
Results: The frequency of secondary enucleation was significantly lower in the endoresection group. At the same time viusal acuity could be obtained at a higher level in the surgery group.
Conclusion: Eyes with large uvela melanomas can be salvaged by stereotactic radiotherapy followed by endoresection and adjuvant brachtherapy.