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22nd Annual Meeting of the German Retina Society

German Retina Society

26.06. - 27.06.2009, Berlin

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Development of the visual acuity after ILM-peeling for epiretinal gliosis with and without staining with indocyanine green

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  • Andreas Schüler - Eye Clinic Universitaetsallee, Bremen
  • S. Bopp - Eye Clinic Universitaetsallee, Bremen
  • K. Lucke - Eye Clinic Universitaetsallee, Bremen

German Retina Society. 22nd Annual Meeting of the German Retina Society. Berlin, 26.-27.06.2009. Düsseldorf: German Medical Science GMS Publishing House; 2009. DocRG2009-27

doi: 10.3205/09rg28, urn:nbn:de:0183-09rg285

This is the English version of the article.
The German version can be found at: http://www.egms.de/de/meetings/rg2009/09rg28.shtml

Published: June 29, 2009

© 2009 Schüler et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Indocyanine-green (ICG) assisted peeling of the internal limiting membrane (ILM) is, despite the ongoing debate about the toxicity of this dye, still widely used. This retrospective case control study analyzed the effect of the staining of the ILM with ICG on the postoperative development of the visual acuity in eyes with epiretinal gliosis.

Methods: The visual outcome of surgeries, performed in 2001 without using of a dye were compared with surgeries performed in 2007 with ICG-assisted ILM-peeling. All eyes were treated with a combined phakoemulsification with IOL-implantation and a vitrectomy with membrane- and ILM-peeling.

Results: Preoperative LogMar-visual acuity was in the group without staining (n=75) 0,46±0,21 and in the group with ICG-assisted ILM-peeling (n=78) 0,37±0,23. Six weeks after surgery was the increase of LogMar-visual acuity in the group without ILM-staining –0,1±0,16 compared to –0,035±0,23 in the group treated with ICG-staining (p=0,05). Long term increase of visual acuity was in the group without ILM-staining after a mean follow-up of 13,7 months –0,17±0,23 and in the group with ICG-assisted ILM-peeling after a mean follow-up of 10,2 months –0,10±0,22 (p=0,009).

Summary: Intraoperative staining of the ILM with ICG during vitrectomy for epiretinal gliosis resulted in a slower recovery and a significant lower long-term increase of the postoperative visual acuity. This study showed a clinically measurable effect of ICG on the visual outcome and emphasizes the relevance of the discussion about the toxic effect of the used dyes.