gms | German Medical Science

22nd Annual Meeting of the German Retina Society

German Retina Society

26.06. - 27.06.2009, Berlin

AMD-Prophylaxis: What is the influence of vitamines and supplements?

Meeting Abstract

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  • Daniel Pauleikhoff - Augenabteilung am St. Franziskus Hospital Münster
  • M. Zeimer - Augenabteilung am St. Franziskus Hospital Münster

German Retina Society. 22nd Annual Meeting of the German Retina Society. Berlin, 26.-27.06.2009. Düsseldorf: German Medical Science GMS Publishing House; 2009. DocRG2009-01

DOI: 10.3205/09rg01, URN: urn:nbn:de:0183-09rg010

This is the translated version of the article.
The original version can be found at: http://www.egms.de/de/meetings/rg2009/09rg01.shtml

Published: June 29, 2009

© 2009 Pauleikhoff et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

In the last 15 years large interventional studies (ARED-study) have investigated the possible protective effect of vitamins and supplements on the progression of early AMD towards late AMD. The 10 year folow-up data could demonstrate an rapidly increasing risk for progression according to specific early AMD characteristics, which could be classified with scores (soft drusen each eye 1 score, hyperpigmentations each eye 1 score, unilateral late AMD 2 scores; resulting individual score 0-4; 10-progression-data: AREDS-score 0=1.1%; score 1=8.5%; score 2=26.8%; score 3=54.2%; score 4=72.1%). Patients with score between 2-4 are therefore on a specific high risk for progression. This risk could be reduced appr. at 10% in each group by the application of the AREDS-medication. This effect is a clinical significant and for patients with AREDS-scores 2-4 this medications is recommended. In addition omega-3-faty-acids and may have a protective effect on the progression of early AMD towards CNV and also lutein and zexanthin may be protective. The influence of these substances on the progression of early AMD is evaluated in further interventional studies (AREDS-2).