gms | German Medical Science

21st Annual Meeting of the German Retina Society and 8th Symposium of the International Society of Ocular Trauma (ISOT)

German Retina Society
International Society of Ocular Trauma

19.06. - 22.06.2008, Würzburg

Avastin as therapeutic approach for a neovascularization derived from the foveal arcade in proliferative diabetic retinopathy

Meeting Abstract

  • Bernd Junker - Freiburg/Germany
  • A. Pielen - Freiburg/Germany
  • N. Feltgen - Freiburg/Germany
  • U. Hansen - Freiburg/Germany

Retinologische Gesellschaft. International Society of Ocular Trauma. 21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem 8. Symposium der International Society of Ocular Trauma. Würzburg, 19.-22.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocISOTRG2008P24

The electronic version of this article is the complete one and can be found online at:

Published: June 18, 2008

© 2008 Junker et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Central neovascularization from the foveal arcade is a rare finding even in severe proliferative diabetic retinopathy (PDR). We report the course of such a neovascularization after treatment with a single dose of intravitreal Bevacizumab.

Methods: Case report

Results: A 37-year old female patient presented 3 months after panretinal laser therapy in PDR and central neovascularization. Visual acuity (VA) was 0.8 in the treated eye. Ophthalmoscopy showed vessels in the foveal area. Fluorescein angiography (FAG) verified an enlarged neovascularization that derived from the foveal arcade with leakage after 10 minutes and could also be demonstrated by OCT. We decided to administer a single intravitreal injection of bevacizumab. One month later VA was still 0.8. Ophthalmoscopy showed a fibrotic neovascularization whereas OCT-findings were unchanged. No sign of perfusion or leakage could be seen in FAG.

Conclusion: The present case report suggests the therapeutical efficacy of bevacizumab in a patient with PDR and central neovascularization.