Article
Avastin as therapeutic approach for a neovascularization derived from the foveal arcade in proliferative diabetic retinopathy
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Published: | June 18, 2008 |
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Outline
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Central neovascularization from the foveal arcade is a rare finding even in severe proliferative diabetic retinopathy (PDR). We report the course of such a neovascularization after treatment with a single dose of intravitreal Bevacizumab.
Methods: Case report
Results: A 37-year old female patient presented 3 months after panretinal laser therapy in PDR and central neovascularization. Visual acuity (VA) was 0.8 in the treated eye. Ophthalmoscopy showed vessels in the foveal area. Fluorescein angiography (FAG) verified an enlarged neovascularization that derived from the foveal arcade with leakage after 10 minutes and could also be demonstrated by OCT. We decided to administer a single intravitreal injection of bevacizumab. One month later VA was still 0.8. Ophthalmoscopy showed a fibrotic neovascularization whereas OCT-findings were unchanged. No sign of perfusion or leakage could be seen in FAG.
Conclusion: The present case report suggests the therapeutical efficacy of bevacizumab in a patient with PDR and central neovascularization.