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21st Annual Meeting of the German Retina Society and 8th Symposium of the International Society of Ocular Trauma (ISOT)

German Retina Society
International Society of Ocular Trauma

19.06. - 22.06.2008, Würzburg

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Retinal pigment epithelial rip in a twelve-years-old girl after intravitreal injection of ranibizumab for choroidal neovascularisation

Meeting Abstract

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  • Isabel Oberacher-Velten - Regensburg/Germany
  • K. Hufendiek - Regensburg/Germany
  • C. Framme - Regensburg/Germany
  • H. Helbig - Regensburg/Germany

Retinologische Gesellschaft. International Society of Ocular Trauma. 21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem 8. Symposium der International Society of Ocular Trauma. Würzburg, 19.-22.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocISOTRG2008V130

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/rg2008/08rg131.shtml

Published: June 18, 2008

© 2008 Oberacher-Velten et al.
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Background: Retinal pigment epithelial rips in children are very unusual and have not been further reported so far.

Case report: A twelve-years-old girl suffered from inner ear deafness and retinopathy presumably due to asymptomatic intrauterine varizella-zoster-infection. When she presented first with visual loss in the OD, a minimal classic CNV was diagnosed. At that time, no signs of retinal pigment epithelial rip were found. After written informed consent was obtained from her parents, the child was treated by three consecutive intravitreal injections with ranibizumab 0.05 mg. Three weeks after the first injection, a retinal pigment epithelial rip was found. The two following injections were continued as predetermined. Visual acuity improved from 20/400 to 20/50. Optical coherence tomography showed significant reduction of intraretinal and subretinal fluid.

Conclusions: A retinal pigment epithelial rip which is very unusual for children developed three weeks after intravitreal injection of ranibizumab. Improvement of visual acuity however occurred after two further injections as previously reported in adults.